Metabolism

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Where in the cell does Pentose phosphate pathway occur?

Burning one glucose runs through four stages: glycolysis in the cytoplasm (net 2 ATP and 2 NADH), the pyruvate dehydrogenase step and the citric acid cycle in the mitochondrial matrix, and the electron transport chain on the inner mitochondrial membrane, where oxygen is the final electron acceptor. The total is roughly 30 to 32 ATP per glucose.

Three modes: Location (cytoplasm, matrix, or inner membrane), Net yield (the ATP and electron carriers each pathway produces), and Key enzyme (the rate-limiting or signature enzyme, such as PFK-1 for glycolysis).

The module also covers fermentation, the pentose phosphate pathway, gluconeogenesis, and beta-oxidation so the side routes off glucose are in view too.